Chronology of KSC and KSC Related Events for 1997

This document is intended to serve as a record of KSC events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and described by the KSC Library Archivist for KSC Library Services Contractor, Sherikon Space Systems, Inc

Chronology of KSC and KSC Related Events for 1996

The document is intended to serve as a record of KSC events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and described by the KSC Library Archivist for KSC Library Services Contractor Sherikon Space Systems, Inc

Chronology of KSC and KSC Related Events for 2005

This document is intended to serve as a record of KSC events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and described by the KSC Library .Archivist for KSC Library Services Contractor, InDyne, Inc

Chronology of KSC and KSC Related Events for 2011

This document is intended to serve as a record of KSC events and is a reference source for historian and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and compiled by the KSC Library Archivist for KSC Library Services Contractor, Abacus Technology Corporation

Chronology of KSC and KSC Related Events for 2008

This document is intended to serve as a record of KSC events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and compiled by the KSC Library Archivist for KSC Library Services Contractor, Abacus Technology Corporation

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Chronology of KSC and KSC Related Events for 1999

This document is intended to serve as a record of Kennedy Space Center (KSC) events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and described by the KSC Library Archivist for KSC Library Services Contractor InDyne, Inc

Chronology of KSC and KSC Related Events for 2002

This document is intended to serve as a record of KSC events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and described by the KSC Library Archivist for KSC Library Services Contractor, InDyne, Inc

Chronology of KSC and KSC Related Events for 2003

This document is intended to serve as a record of KSC events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and described by the KSC Library Archivist for KSC Library Services Contractor, InDyne, Inc

Chronology of KSC and KSC Related Events for 2000

This document is intended to serve as a record of Kennedy Space Center (KSC) events and is a reference source for historians and other researchers. Arrangement is by day and month and individual articles are attributed to published sources. Materials were researched and described by the KSC Library Archivist with assistance from KSC Library Librarians for KSC Library Services Contractor InDyne, Inc